323 - Candida nivariensis isolates from a pregnant patient. Molecular identification using sequencing and MALDI-TOF
323 - Candida nivariensis isolates from a pregnant patient. Molecular identification using sequencing and MALDI-TOF
Marco Passera, Silvia Corbellini, Giorgia Cavalli, Francesca Vailati, Luigi Frigerio, Claudio Farina
Int J Clin Exp Pathol 2016;9(10):10774-10777
Abstract: Candida nivariensis is a recently described yeast, phenotypically indistinguishable from Candida glabrata. We report a vaginal isolation of C. nivariensis from an Indian pregnant woman, hospitalized for premature ruptured membranes. The isolate was initially incorrectly identified as C. glabrata using Vitek 2 system and then retested by MALDI-TOF. Candida nivariensis identification was then confirmed by sequencing. The current study revealed an high MIC to Fluconazole (2 mcg/mL), in according to previous studies. Candida nivariensis is a causative agent of vulvovaginal candidiasis, but its real incidence in our continent may be underestimated due to lack of adequate molecular or mass spectroscopy surveillance strategies. Antifungal susceptibility of this species requires further study.
