Luigi Frigerio

Gynecology and Urology I, Second World Week of Professional Updating in Surgery.
Monduzzi Ed. pag. 7-10. 1990
( in coll. S. Garsia, L. Busci, A. Pirondini, G. Pifarotti, A. Ferrari )
Summary: Between 1975 and 1986, Second-Look Laparotomy(SLL) to evaluate disease status was performed in 87 patients originally presenting with epithelial ovarian carcinoma. Surgical and histologic assessment did not reveal persistent disease in 34 patients ( 39% ). The 3-years survival, by Kaplan and Meier calculation, was 73.5% after negative SLL versus 32% after positive SSL (p<0.01). Seventeen of the 24 patients declared free of disease after original surgery remained negative at SLL (70.8%), 7 cases out of 12 with disease less than 2 cm resulted negative at reexploration (58.3%), but only 8 of 31 patints with tumor greater than 2 cm were fre of disease at the time of SLL (25.8%), (p<0.01). Recurrent carcinoma was subsequently documented in 13 of 34 patients (38.2%) that were negative at SLL. Additional diagnostic effort will be carried out to increase our knowledge about this severe disease.