Luigi Frigerio

It. Journal of Gynecologic and Obstetrics. Vol. 2, pag. 19-24. 1990
( in coll. L. Busci, S. Garsia, A. Pirondini, A. Ferrari )
Summary: Between 1975 and 1986, second look laparotomy (SLL) to evaluate desease status was performed in 87 patients originally presenting with epithelial ovarian carcinoma. Surgical and histologic assessment did not reveal persistent desease in 34 patients (39%). The 3-years survival, by Kaplan-Meier calculation, was 73.5% after negative SLL versus 32% after posotive SLL ( p< 0.01). Residual tumor (RT) was absent after original operation in 24 patients (35.8%), in 12 cases (17.9%) RT was less than 2 cm, and in 31 cases (46.2%) RT was more than 2 cm. Negative SLL is related to RT at primary surgery. The merit of reassessment surgery is the prognostic value of this procedure: the mortality at 3 years after primary surgery was 26.5% of cases with negative SLL and 68% after positive SLL( p< 0.01).