Luigi Frigerio

International Gynecologic Cancer Society. Third Biennal Meeting. Australia, 22-26 Settembre 1991
( in coll. L. Busci, A. Pirondini, G. Banfi, A. Ferrari )
Summary: In patients affected by cervical cancer at the stages Ib IIa, a reduced 5-yrs survival is related to vascular invasion (35.7%) and limph node involvement (43.5%) despite large adoption of adjuvant radiotherapy after radical hysterectomy. In more than 1/3 of these patients the sites of failure occurred outside the treatment area. These, then, would give more definitive evidence with regard to the need for systemic adjuvant therapy in high risk patients. More than 1 high risk prognostic factors, but not nodes involvement were present in 18 patients and 5 yrs survival was 77.7% vs. 80.3% in the patients with only 1 high risk factor (n.s.). The opportunity of any adjuvant post-operative treatment is questionable in other subgroups of patients with secondary factors of risk.